gene_symbol
CD79B
hgnc_id
HGNC:1699
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD79b ADC binds CD79b on B cells, is internalized, linker is cleaved, releasing MMAE that inhibits tubulin polymerization, causing G2/M arrest and apoptosis of the target cell.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Target of antibody moiety on B-cell surface
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05831865
disease_id_num_tar_ref
5699
drug_id_num_tar_ref
15481