gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Epcoritamab binds CD3 on T cells to activate and redirect them to CD20+ B cells, which are killed via perforin/granzyme. CD3+ T cells are not targeted for killing.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
CD3 multi-subunit T-cell receptor complex
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05578976
disease_id_num_tar_ref
5717
drug_id_num_tar_ref
15534