gene_symbol
KIT
hgnc_id
HGNC:6342
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Blocks SCF–c-Kit signaling on hematopoietic stem/progenitor cells, removing survival signals and causing apoptosis/depletion; Fc-mediated clearance may contribute.
enzyme_product
On
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Receptor tyrosine kinase; blocks stem cell factor (SCF/KITLG) binding/signaling on hematopoietic stem/progenitor cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05600907
disease_id_num_tar_ref
5730
drug_id_num_tar_ref
15579