gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Bispecific antibody binds CD20 on B cells and CD3 on T cells, crosslinking them to activate T cells and induce perforin/granzyme-mediated killing of CD20+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell surface antigen
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05615636
disease_id_num_tar_ref
5739
drug_id_num_tar_ref
15596