gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Mosunetuzumab binds CD3ε on T cells to recruit and activate them against CD20+ B cells; T cells expressing CD3 are effectors, not targets, and are not directly killed by the drug.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
T-cell receptor CD3 complex subunit on T cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05615636
disease_id_num_tar_ref
5739
drug_id_num_tar_ref
15596