gene_symbol
IL10RA
hgnc_id
HGNC:5964
binding_type
receptor ligand recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Not targeted. The CAR-NK cells recognize CD19, not IL-10 receptor alpha; killing occurs only upon CD19 engagement via NK perforin/granzyme-mediated cytolysis of CD19+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
IL-10 binds IL10RA to modulate inflammation and the tumor microenvironment
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06707259
disease_id_num_tar_ref
1
drug_id_num_tar_ref
1