gene_symbol
CTAG1B
hgnc_id
HGNC:2491
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
TCR-engineered autologous T cells recognize NY-ESO-1 peptide presented by HLA-A2 on tumor cells and directly kill them via perforin/granzyme-mediated cytotoxicity (and Fas-FasL apoptosis).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
HLA-A*02:01-restricted peptide epitope (e.g., NY-ESO-1 157-165, SLLMWITQC)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05989828
disease_id_num_tar_ref
54
drug_id_num_tar_ref
130