gene_symbol
MSLN
hgnc_id
HGNC:7371
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-mesothelin CAR T cells bind MSLN on target cells, activate, and kill via perforin/granzyme-mediated cytolysis and death receptor pathways.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface GPI-anchored tumor-associated glycoprotein
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05775666
disease_id_num_tar_ref
5782
drug_id_num_tar_ref
15706