gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Epcoritamab engages CD3 on T cells to activate them and bring them to CD20+ B cells; the T cells then kill the CD20-expressing cells via perforin/granzyme, not the CD3+ T cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
T-cell receptor/CD3 complex component
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06510361
disease_id_num_tar_ref
5807
drug_id_num_tar_ref
15763