gene_symbol
CD276
hgnc_id
HGNC:19137
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR γδ T cells bind B7‑H3 on target cells and, upon CAR activation, directly kill them via cytotoxic degranulation (perforin/granzyme) leading to apoptosis/lysis, with supportive cytokine effects.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06372236
disease_id_num_tar_ref
5839
drug_id_num_tar_ref
15860