gene_symbol
MSLN
hgnc_id
HGNC:7371
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
MSLN-specific CAR T cells bind mesothelin on target cells, form an immune synapse, and kill via perforin/granzyme-mediated cytolysis (with supportive cytokine effects).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
cell-surface tumor-associated antigen
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06760364
disease_id_num_tar_ref
486
drug_id_num_tar_ref
1343