gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Binds CD19 on target cells and engages Fcγ receptor–bearing effector cells to mediate antibody-dependent cellular cytotoxicity and phagocytosis, depleting CD19+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Fc-engineered antibody enhances ADCC/ADCP via Fcγ receptors
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05993611
disease_id_num_tar_ref
5845
drug_id_num_tar_ref
15871