gene_symbol
IL3RA
hgnc_id
HGNC:6012
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-engineered NK cells bind CD123 on target cells, triggering NK activation and degranulation (perforin/granzyme) and death-receptor signaling, causing lysis/apoptosis of CD123-positive cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06006403
disease_id_num_tar_ref
5869
drug_id_num_tar_ref
15931