gene_symbol
CD7
hgnc_id
HGNC:1695
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD7 CAR-T cells recognize CD7 on target cells; CAR signaling activates T-cell effector functions, releasing perforin and granzymes (and Fas–FasL signaling), leading to lysis/apoptosis of CD7+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface antigen on T-lineage cells; also on some NK cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06064903
disease_id_num_tar_ref
5899
drug_id_num_tar_ref
16002