gene_symbol
CD2
hgnc_id
HGNC:1639
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Thymoglobulin antibodies bind CD2 on T cells, triggering complement-dependent lysis and Fc-mediated ADCC/ADCP, and inducing apoptosis, thereby depleting CD2+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
T-cell adhesion/costimulatory molecule
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06066255
disease_id_num_tar_ref
5901
drug_id_num_tar_ref
16008