gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD19 CAR gamma-delta T cells bind CD19 on B cells, activate via the CAR, and kill targets through perforin/granzyme-mediated cytolysis (apoptosis).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface B-lineage antigen (B cells, plasmablasts)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06417398
disease_id_num_tar_ref
493
drug_id_num_tar_ref
1362