gene_symbol
CD4
hgnc_id
HGNC:1678
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Polyclonal IgG binds CD4 on T cells and induces complement-dependent lysis and Fc-receptor–mediated ADCC/ADCP, with apoptosis, leading to depletion of CD4+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
T-cell co-receptor
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06066255
disease_id_num_tar_ref
5901
drug_id_num_tar_ref
16008