gene_symbol
DLL3
hgnc_id
HGNC:2909
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
A BiTE that bridges CD3 on T cells to DLL3 on target cells, forming an immune synapse and triggering T cell–mediated killing via perforin/granzyme release and cytokine-driven cytotoxicity.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Notch pathway ligand overexpressed on SCLC cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06117774
disease_id_num_tar_ref
5902
drug_id_num_tar_ref
16009