gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD19 CAR T cells bind CD19, activate, and kill target cells via perforin/granzyme-mediated cytolysis (with IL-18 enhancing CAR-T expansion and activity).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell surface antigen on malignant and normal B cells recognized by anti-CD19 CAR
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05989204
disease_id_num_tar_ref
5911
drug_id_num_tar_ref
16032