gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Neoantigen-specific TCRs on the reinfused autologous T cells recognize the peptide–HLA class I complex and directly kill target cells via cytotoxic T cell mechanisms (perforin/granzyme-mediated apoptosis, plus Fas–FasL).
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
CD8+ TCR recognition of peptide–MHC-I complex
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05685004
disease_id_num_tar_ref
5914
drug_id_num_tar_ref
16039