gene_symbol
CD70
hgnc_id
HGNC:11937
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CD70-specific CAR T cells bind CD70 on target cells and kill them via T-cell cytotoxicity, primarily perforin/granzyme-mediated lysis after CAR engagement.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
tumor cell surface antigen; TNF ligand family member (TNFSF7)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05353530
disease_id_num_tar_ref
5934
drug_id_num_tar_ref
16080