gene_symbol
CD38
hgnc_id
HGNC:1667
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Binds CD38 on target cells; Fc engagement triggers ADCC, ADCP, and CDC, and can induce direct apoptosis of CD38+ cells.
enzyme_product
On
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Type II transmembrane ectoenzyme (ADP-ribosyl cyclase/cADPR hydrolase)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05907759
disease_id_num_tar_ref
5946
drug_id_num_tar_ref
16122