gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
TILs recognize the neoantigen–HLA class II complex via their TCR and directly kill the target cell through perforin/granzyme release and IFN-γ–mediated cytotoxicity.
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
TCR-dependent; CD4-restricted; HLA-DR/HLA-DQ/HLA-DP
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06145802
disease_id_num_tar_ref
5975
drug_id_num_tar_ref
16207