gene_symbol
MICA
hgnc_id
HGNC:7090
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
NKG2D CAR on NK cells binds MICA on target cells, activating NK cytotoxicity with perforin/granzyme release and death receptor–mediated apoptosis (TRAIL/Fas).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Stress-induced NKG2D ligand
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06503497
disease_id_num_tar_ref
5976
drug_id_num_tar_ref
16211