gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Teclistamab binds CD3 on T cells to activate them and crosslink to BCMA+ myeloma cells; CD3+ T cells are not killed—rather, they kill BCMA-expressing targets via perforin/granzyme release.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
T-cell receptor complex component
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05572229
disease_id_num_tar_ref
6016
drug_id_num_tar_ref
16313