gene_symbol
FOLH1
hgnc_id
HGNC:3788
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Radiolabeled anti-PSMA antibody binds PSMA and delivers 177Lu beta radiation to the target cell, causing DNA double-strand breaks and cell death (with cross-fire to nearby cells).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface membrane enzyme (glutamate carboxypeptidase II/GCPII) targeted by radiolabeled monoclonal antibody
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT04876651
disease_id_num_tar_ref
6059
drug_id_num_tar_ref
16418