gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD20 antibody binds CD20 on B cells and induces complement-dependent cytotoxicity and Fc-mediated ADCC (and apoptosis), leading to depletion of CD20+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Type I anti-CD20 monoclonal antibody; binds the large extracellular loop of CD20
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05962840
disease_id_num_tar_ref
6073
drug_id_num_tar_ref
16455