gene_symbol
FOLR1
hgnc_id
HGNC:3791
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
The ADC binds FRα on tumor cells, is internalized via receptor-mediated endocytosis, and releases an intracellular cytotoxic payload that kills the FRα-expressing cell.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
GPI-anchored cell-surface receptor; internalized via FRα-mediated endocytosis
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05498597
disease_id_num_tar_ref
6074
drug_id_num_tar_ref
16457