gene_symbol
CD44
hgnc_id
HGNC:1681
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells recognize CD44 on target cells, activating CD3ζ/co-stimulatory signaling and killing bound cells via perforin/granzyme release and death-receptor pathways.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Glioma/cancer stem-like cell marker; hyaluronan receptor
trial_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05577091
disease_id_num_tar_ref
6076
drug_id_num_tar_ref
16459