gene_symbol
PROM1
hgnc_id
HGNC:9454
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells bind CD133 via the CAR and directly lyse target cells through perforin/granzyme release and Fas–FasL–mediated apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Glioma/cancer stem-like cell marker
trial_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05577091
disease_id_num_tar_ref
6076
drug_id_num_tar_ref
16459