gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Bispecific BCMA×CD3 antibody redirects and activates T cells against BCMA+ cells, causing perforin/granzyme-mediated cytolysis (with cytokine release) of the target cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface receptor on plasma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06140524
disease_id_num_tar_ref
511
drug_id_num_tar_ref
1417