gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Linvoseltamab uses CD3 on T cells to activate them while binding BCMA on target cells; activated T cells kill BCMA+ cells via perforin/granzyme cytotoxicity, not CD3+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
T-cell receptor CD3 complex subunit on T cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06140524
disease_id_num_tar_ref
511
drug_id_num_tar_ref
1417