gene_symbol
HLA-DRB1
hgnc_id
HGNC:4948
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Engineered T cells kill cells that present the HPV18-derived peptide in complex with HLA‑DRB1*09:01 via TCR activation and perforin/granzyme-mediated lysis; HLA‑DRB1*09:01 expression alone is not sufficient.
enzyme_product
Off
epitope
Off
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
Presents HPV18 peptide epitope
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05952947
disease_id_num_tar_ref
6152
drug_id_num_tar_ref
16671