gene_symbol
CD22
hgnc_id
HGNC:1643
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CD22-targeted CAR T cells bind CD22 on tumor cells, activate via CD3ΞΆ/co-stimulatory signaling, and kill through perforin/granzyme release and death-receptor (e.g., Fas/FasL) pathways.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell surface antigen
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06202885
disease_id_num_tar_ref
6155
drug_id_num_tar_ref
16679