gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Elranatamab bridges CD3 on T cells and BCMA on target cells, forming an immune synapse that activates T-cell cytotoxicity (perforin/granzyme-mediated killing) of BCMA-positive cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface receptor on malignant plasma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05932290
disease_id_num_tar_ref
6173
drug_id_num_tar_ref
16738