gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-GD2 mAb binds GD2 on tumor cells and recruits immune effectors to kill via Fc-mediated ADCC (e.g., NK cells) and complement-dependent cytotoxicity (CDC).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
cell-surface glycolipid (ganglioside)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06047535
disease_id_num_tar_ref
6181
drug_id_num_tar_ref
16759