gene_symbol
C1QB
hgnc_id
HGNC:1242
binding_type
receptor ligand recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
XON7 binds tumor antigens on cancer cells and kills them via Fc-mediated ADCC/ADCP and complement-dependent cytotoxicity (C1q activation). Complement C1q B chain is an effector component, not the binding target; cells expressing it are not directly killed by the drug.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Fc–C1q interaction initiating classical complement; CDC.
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06154291
disease_id_num_tar_ref
6196
drug_id_num_tar_ref
16795