gene_symbol
C1QC
hgnc_id
HGNC:1245
binding_type
receptor ligand recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
C1q C chain is a complement component that binds the antibody Fc to activate CDC against antibody-coated tumor cells. XON7 does not target C1q; cells expressing C1q are not directly killed.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Fc–C1q interaction initiating classical complement; CDC.
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06154291
disease_id_num_tar_ref
6196
drug_id_num_tar_ref
16795