gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
CD3 engagement activates and redirects T cells; these T cells then kill CD20-positive B cells via perforin/granzyme-mediated cytotoxicity. CD3ε-expressing T cells are not targeted for killing.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Epsilon chain of the CD3/TCR complex on T cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06084936
disease_id_num_tar_ref
6198
drug_id_num_tar_ref
16801