gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Binds CD20 on B cells and triggers complement-dependent cytotoxicity and Fc-mediated ADCC; can also induce apoptosis, leading to lysis/depletion of CD20+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-lymphocyte surface antigen; binds extracellular loops
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05776888
disease_id_num_tar_ref
6228
drug_id_num_tar_ref
16885