gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Infused TILs recognize HPV E6/E7 peptides via native TCRs on antigen-presenting tumor cells and induce apoptosis via perforin/granzyme cytolysis (and Fas–FasL), supported by cytokines such as IFN-γ.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
MHC class II–restricted peptide–HLA complex
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06241781
disease_id_num_tar_ref
537
drug_id_num_tar_ref
1482