gene_symbol
CD38
hgnc_id
HGNC:1667
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Binds CD38 on target cells and induces complement-dependent cytotoxicity, antibody-dependent cellular cytotoxicity (via NK cells), antibody-dependent cellular phagocytosis (by macrophages), and can trigger apoptosis, killing CD38+ cells.
enzyme_product
On
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Type II transmembrane ectoenzyme (NADase/ADP-ribosyl cyclase)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06455748
disease_id_num_tar_ref
544
drug_id_num_tar_ref
1500