gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
BCMA-targeted CAR T cells bind BCMA on plasmablasts/plasma cells and induce T-cell–mediated killing via perforin/granzyme release and death-receptor pathways.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface receptor on plasmablasts and long-lived plasma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06497387
disease_id_num_tar_ref
547
drug_id_num_tar_ref
1506