gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Vaccine induces anti-Globo H antibodies that bind Globo H on tumor cells and trigger complement-dependent cytotoxicity and antibody-dependent cellular cytotoxicity (ADCC); vaccine-elicited T-cell responses may also contribute.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface glycolipid TACA on epithelial tumors; target of vaccine-induced antibodies
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06490198
disease_id_num_tar_ref
561
drug_id_num_tar_ref
1552