gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The vaccine induces anti–Globo H antibodies that mediate ADCC and complement-dependent cytotoxicity against Globo H–expressing tumor cells; CRM197 is only a carrier protein and is not a killing target.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Carrier protein providing Th cell epitopes; processed and presented via MHC class II on APCs
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06490198
disease_id_num_tar_ref
561
drug_id_num_tar_ref
1552