gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Infused autologous TILs recognize tumor neoantigen peptide–MHC I via their TCR and directly kill target cells through perforin/granzyme-mediated apoptosis (and Fas–FasL), supported by IL-2.
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
TCR-dependent recognition of patient-specific pMHC-I epitopes on tumor cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06342336
disease_id_num_tar_ref
65
drug_id_num_tar_ref
157