gene_symbol
CD22
hgnc_id
HGNC:1643
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
The bispecific antibody bridges CD3 on T cells to CD22 on target B cells, forming an immune synapse and triggering T‑cell–mediated cytolysis (perforin/granzyme-induced apoptosis) of CD22+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell surface antigen (Siglec-2)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06660563
disease_id_num_tar_ref
563
drug_id_num_tar_ref
1558