gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The bispecific binds CD3E on T cells to activate and redirect them to kill CD22-positive B cells; CD3E-expressing T cells are not the lytic target.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
T-cell receptor-CD3 complex subunit on T cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06660563
disease_id_num_tar_ref
563
drug_id_num_tar_ref
1558