gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Autologous TILs recognize HPV E6/E7 peptide–HLA class I via native TCRs and induce tumor cell death via perforin/granzyme-mediated cytolysis (and death receptor pathways).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Relevant for HPV-positive head and neck cancer; viral pMHC target
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06190275
disease_id_num_tar_ref
580
drug_id_num_tar_ref
1617