gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Adoptively transferred TCR-specific CTLs recognize the AML1-ETO junctional peptide on HLA class I and directly lyse target cells via perforin/granzyme-mediated apoptosis (with possible Fas/FasL contribution).
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
HLA-A*11:01–restricted peptide-HLA class I complex
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06499025
disease_id_num_tar_ref
592
drug_id_num_tar_ref
1664